Mac and Cheese Meatloaf Casserole

Combining two family favorites—creamy mac and cheese and savory meatloaf—this Mac and Cheese Meatloaf Casserole is a game-changer. Perfect for weeknight dinners or weekend gatherings, this dish is comforting, hearty, and packed with flavor. Whether you’re serving a crowd or looking for leftovers to enjoy, this recipe delivers a satisfying blend of textures and tastes.

Ground beef mixture being pressed into a casserole dish for the meatloaf layer.
Press the seasoned meat mixture into the dish for a hearty and flavorful base.

Ingredients for Mac and Cheese Meatloaf Casserole

For the Meatloaf Layer:

  • 1 1/2 pounds ground beef (80/20 blend)
  • 1 small onion, finely diced
  • 2 cloves garlic, minced
  • 1 cup breadcrumbs
  • 1 large egg
  • 1/2 cup milk
  • 2 tablespoons Worcestershire sauce
  • 1 teaspoon salt
  • 1/2 teaspoon black pepper
  • 1/2 cup ketchup (for the topping)

For the Mac and Cheese Layer:

  • 2 cups elbow macaroni (uncooked)
  • 2 tablespoons unsalted butter
  • 2 tablespoons all-purpose flour
  • 2 cups whole milk
  • 2 cups shredded sharp cheddar cheese
  • 1/2 cup shredded mozzarella cheese
  • 1/2 teaspoon garlic powder
  • 1/4 teaspoon paprika
  • Salt and pepper to taste

Optional Garnishes:

  • Fresh parsley, chopped
  • A sprinkle of breadcrumbs for crunch

Step-by-Step Instructions to Make Mac and Cheese Meatloaf Casserole

1. Preheat the Oven and Prepare the Baking Dish

  • Preheat your oven to 375°F (190°C).
  • Grease a 9×13-inch baking dish lightly with cooking spray or butter.

2. Prepare the Meatloaf Layer

  • In a large mixing bowl, combine the ground beef, diced onion, garlic, breadcrumbs, egg, milk, Worcestershire sauce, salt, and pepper.
  • Mix gently until just combined. Overmixing can make the meatloaf tough.
  • Press the meat mixture evenly into the bottom of the prepared baking dish to form a solid layer.
  • Spread a thin layer of ketchup evenly over the top of the meatloaf for added flavor and moisture.

Tip: Use a spatula to level the meatloaf layer for an even surface.

3. Cook the Macaroni

  • While the meatloaf layer is baking, bring a large pot of salted water to a boil.
  • Cook the elbow macaroni according to package directions until al dente (firm to the bite). Drain and set aside.

4. Prepare the Cheese Sauce

  • In a medium saucepan, melt the butter over medium heat.
  • Whisk in the flour to create a roux and cook for 1–2 minutes until golden brown.
  • Gradually whisk in the milk, stirring constantly to prevent lumps. Let the mixture simmer for 3–4 minutes until slightly thickened.
  • Reduce the heat and stir in the shredded cheddar and mozzarella cheeses until smooth and creamy.
  • Season with garlic powder, paprika, salt, and pepper to taste.

5. Combine the Mac and Cheese Layer

  • Mix the cooked macaroni into the cheese sauce, ensuring the pasta is fully coated.
  • Carefully spoon the mac and cheese mixture over the meatloaf layer in the baking dish. Spread it evenly with a spatula.

6. Bake the Casserole

  • Place the dish in the preheated oven and bake for 25–30 minutes, or until the meatloaf is fully cooked (internal temperature of 160°F) and the mac and cheese is bubbling.
  • For a golden, crispy top, broil the casserole for an additional 2–3 minutes.

7. Serve and Garnish

  • Remove the casserole from the oven and let it cool for 5 minutes.
  • Garnish with fresh parsley or a sprinkle of breadcrumbs for added texture.
  • Slice and serve warm, enjoying the creamy mac and cheese paired with the savory meatloaf layer.

Why You’ll Love This Recipe

  1. Two Dishes in One: You get the richness of meatloaf and the creaminess of mac and cheese in every bite.
  2. Family-Friendly: Kids and adults alike love this dish for its comforting flavors and textures.
  3. Make Ahead Option: Prepare the layers ahead of time and bake when ready to serve.
  4. Perfect for Leftovers: This casserole reheats beautifully, making it ideal for busy days.

Tips for the Best Mac and Cheese Meatloaf Casserole

  1. Don’t Overmix the Meatloaf: Mix the ground beef just enough to combine the ingredients. This keeps the meatloaf tender and juicy.
  2. Use Freshly Grated Cheese: Pre-shredded cheese often contains additives that prevent melting. Grate your cheese for the best results.
  3. Add a Crunchy Topping: Sprinkle breadcrumbs or crushed crackers over the mac and cheese layer before baking for a golden, crispy finish.
  4. Monitor Baking Time: Check that the meatloaf reaches an internal temperature of 160°F to ensure it’s fully cooked.

What to Serve with Mac and Cheese Meatloaf Casserole

This hearty casserole pairs well with simple, fresh sides:

  • Steamed Vegetables: Green beans, broccoli, or carrots.
  • Garden Salad: A light salad with a vinaigrette dressing to balance the richness.
  • Garlic Bread: Warm, crispy garlic bread makes the perfect companion.
  • Roasted Potatoes: Add an extra layer of comfort with crispy roasted potatoes.

Frequently Asked Questions (FAQs)

1. Can I make this casserole ahead of time?

Yes! Assemble the casserole, cover it tightly with plastic wrap, and refrigerate for up to 24 hours. Bake when ready.

2. Can I freeze leftovers?

Absolutely. Allow the casserole to cool completely, then portion it into airtight containers. Freeze for up to 3 months. Reheat in the oven at 350°F until warmed through.

3. Can I substitute the ground beef?

Yes. Ground turkey, chicken, or even plant-based meat alternatives work well in this recipe. Adjust seasoning as needed.

4. How do I make the mac and cheese creamier?

Add an extra 1/4 cup of milk or a tablespoon of cream cheese to the cheese sauce for an ultra-creamy texture.

5. Can I add vegetables to the casserole?

Certainly! Stir in sautéed spinach, peas, or diced carrots to the mac and cheese layer for added nutrition and flavor.

Final Thoughts

This Mac and Cheese Meatloaf Casserole combines two comfort food favorites into one showstopping dish. The savory meatloaf layer paired with the creamy, cheesy macaroni creates a satisfying and crowd-pleasing meal. Whether it’s for a busy weeknight dinner or a special occasion, this recipe is sure to become a household favorite.

Try it today and impress your family with this delicious, comforting casserole!
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